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Dapoxetine (dapoxetine) 30 mg, compared to 50% on placebo.

Dapoxetine belongs to a class of medication known as pde5 inhibitors. Men taking showed an improvement in their ability to get and keep an erection versus those who took placebo.

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Dapoxetine
Clinical data
Trade namesPriligy, others (see below)
AHFS/Drugs.comInternational Drug Names
Routes of administrationOral (tablets)
ATC codeG04BX14 ( WHO )
Legal status
Legal statusIn general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability15–76% (mean 42%), T max = 1–1.3 hours
Protein binding>99%
MetabolismLiver (CYP2D6, CYP3A4), kidney (FMO1)
MetabolitesDapoxetine- N -oxide, desmethyldapoxetine, didesmethyldapoxetine
Elimination half-life1.5–1.6 h
ExcretionKidneys [1]

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